Assessment of Bisphenol a in Umbilical Cord Blood and Maternal Blood

Abstract

Bisphenol A (BPA) is an industrial material used to make polycarbonate plastics and epoxy resins. BPA is found to leach from food and beverage containers. However, BPA is an endocrine disruptor that may interfere with the body’s endocrine system and affect development in infants and children. The purpose of this study was to determine the distribution of bisphenol A (BPA) levels in umbilical cord blood and maternal blood. Thirty maternal blood and 39 umbilical cord blood samples during pregnancy and delivery were obtained from the hospitals in this study, respectively. Results demonstrated the detection rates of plasma BPA in pregnant woman and neonates were 26.7% and 51.0%. The maternal BPA concentrations were 0.896 ± 6.80 (mean ± SD) µg/L, with a range from <0.48 to 71.7 µg/L. The neonatal BPA concentrations were 1.86 ± 3.24 µg/L, with a range from <0.48 to 26.8 µg/L. The present study showed the fetus was exposed to BPA through umbilical cord blood. Future research needs to focus on the effects of BPA on fetus growth and development.

Keywords: Bisphenol A, Pregnant woman, Neonates

DOI: 10.7176/JEES/12-3-01

Publication date:March 31^st 2022