Case Report: Disorder of Sex Development 46, XY with Proximal Hypospadias in a 10-Year-Old Twin Boy: Disorder of Sex Development 46, XY with Proximal Hypospadias

Abstract

Hypospadias is a congenital defect in which the opening of the urethra is located on the ventral side of the penis proximal to the tip of the glans penis. The cause of hypospadias is still not clear and believed to have several factors. Hypospadias occurs due to disruption of urethral fold fusion at the 8^th – 15^th week in the uterus which is influenced by dihydrotestosterone. Hypospadias can cause a disorder of sex development according to the conditions. A case of proximal hypospadias was reported to occur in a 10-year-old twin boy accompanied by undescended testis causing a disorder of sex development. For this case, various examinations were carried out along with evaluations to establish the diagnosis, the cause, the treatment plan, and the necessary evaluation.

Keywords: hypospadias, disorder of sex development, undescended testis

DOI: 10.7176/JHMN/80-01

Publication date:September 30^th 2020