Assessment of Endometrial Thickness by TVS for Detection of Endometrial Carcinoma in Women with Post-Menopausal Bleeding

Abstract

Objective: The aim of this study is to evaluate the role of endometrial thickness for detection of endometrial carcinoma in women with post-menopausal bleeding by use of Transvaginal ultrasound.

Method: In this systematic review database by Medline, PubMed, science direct and Obsgyne online library were queried for studies published between 2005 to 2020 by using specific MeSH terms. Abstract from original peer-reviewed prospective Cohort studies that shows endometrial thickness with postmenopausal bleeding by specific ultrasound findings were included in this study.

Results: Clinical data were extracted from 14 studies in which approx. 2500 women included with post-menopausal bleeding and 215(8.6%) cases were diagnose with endometrial carcinoma that shows endometrial thickness greater than 10mm on Transvaginal ultrasound. The prevalence of endometrial cancer was high in patients who had endometrial thickness >9.5 mm. Women with PMB that diagnose with EC had ET was 10 to 16mm.Women with PMB less than 4mm ET not diagnosed with EC.

Conclusion: In this reviewed study we concluded that women with PMB showing ET greater than 10mm on Transvaginal ultrasound diagnosed with Endometrial carcinoma.

Keywords: Endometrial Thickness (ET), Endometrial carcinoma (EC), Post-menopausal bleeding (PMB), Transvaginal Ultrasound (TVS).

DOI: 10.7176/JHMN/82-11

Publication date: November 30^th 2020