The Effect of Dietary Supplements on Wound Healing Progression of Pressure Ulcer Patients:Retrospective Study

Abstract

Background: Trials on dietary supplement for the treatment of pressure ulcers (PUs) have been small. Objective: to investigate the efficiency of the intake of dietary supplement by hospitalized PUs patients on the progression of wound healing. Design: single-center, retrospective trial. 85 adult patients with stage II, III, and IV PUs, were divide them into two  groups group , A  and group B , group A receiving daily the standard hospital diet which is prescribed by physician based on patients’ medical conditions plus one of the wound healing supplement that hospital provides (CUBITAN and ABOUND) and  group B receiving daily the standard hospital diet and  kept without any dietary supplement due to the contraindication of the dietary supplement with their medical conditions. the progression in wound size and nutritional parameters (hydration status, total energy, and protein intake during were documented. Results: treatment group (n = 47) resulted in a greater increase in serum albumin level ([25.1 ± 5.2 to 32.2 ± 5.8]; CUBITAN), ([26.3 ± 6.0 to 28.1 ± 5.2]; ABOUND) than with the control groups (n = 38) ([27.3 ± 7.0 to 27.1 ± 6.4]). A more frequent reduction in wound size was also seen in treatment group ([25.0 ± 42.7 to 14.5 ± 28.5]; CUBITAN), ([21.4 ± 55.1 to 15.8 ± 54.4]; ABOUND) than with the control groups (n = 38) ([17.6 ± 27.4 to 17.9 ± 27.4]). No difference was found in terms of the other variables. Conclusion: The wound healing supplement facilitated the healing of pressure ulcers since the total serum albumin and wound healing progression were significantly higher in the groups compared with those in the control group.

Keywords: wound healing supplement, Pressure ulcers.

DOI: 10.7176/JHMN/105-05

Publication date: January 31^st 2023