Nano tube structures by the intercalation of 5Flouro Cytosine with ZnO-layered hydroxide applied as anti fungal

Abstract

y are indeed formed of positively charged brucite-like layer Layered metal hydroxides(LMH) materials are interesting host nano materials for controlled release type drug. They are formed of positively charged brucite –like layer, and exchangeable anions as well as water molecules are situated in the interlayer spaces(10), ZnO nanotube were synthesized by sol-gel reaction between zinc oxide and (5FlouroCytosine), Evolution  of the anion was characterized by UV-VIS spectroscopy,), Fourier  transform  infrared  (FT-IR) spectroscopy technique, X-ray  diffraction  (XRD), Scanning electron microscopy (SEM), Transmission Electronic Microscope (TEM) (AFM).shows  a well crystalline nano tube  structure was formed. Controlled release was fitted with different modules. Antimicrobial activity tests were done on the Candida fungal, the results showed that nano hybrid composite was more sensitive to the fungal inhibition than the uses of free drug in this study.

Keywords: ZnO; nano materials; antimicrobial activity; intercalations.