FREQUENCY OF HYPOMAGNESAEMIA IN PRE TERM LABOUR

Abstract

Objective: To determine the frequency of hypomagnesaemia in women with preterm labour. Study Design: Cross sectional study Settings: This study was carried out in department of obstetrics & gynaecology Nishtar Hospital Multan. Duration of study: This study was conducted from 10^th November 2016 to 10^th May 2017. Subject and methods: A total of 219 pregnant women with singleton pregnancy, preterm labour and parity 1 – 4 were included in the study. Women with history of diabetes, hypertension smoking and polyhhydramnious amniotic fluid index (AFI)>25 cm on ultrasound were excluded. Venous blood was drawn from entire subjects to evaluate the serum magnesium level and sent immediately to laboratory for analysis venous blood samples were obtained by venipuncture and collected in lithium heparin specimen bottles. Data was collected for hypomagnesaemia. Results: age range in this study was from 20 to 40 years with mean age of 30.356±3.60 years, mean parity 1.936± 0.96, mean gravida 2.936 ± 0.96, mean gestational age 32.000±2.25 weeks and mean BMI was 27.337 ± 1.67 kg/m². Majority of the patients were from 20 – 30 years (51.1%). History of preterm delivery was 17.4%. Majority of patients belong to middle economic status (66.2%). Hypomagnesaemia was seen in 37.9% patients. Conclusion: it is concluded that low serum magnesium (hypomagnesaemia) is associated with preterm onset of  labour. Maternal  hypomagnesaemia may be used as a predictor of preterm labour:

Key words: Pregnancy, preterm labour, hypomagnesaemia