FREQUENCY OF RENAL DERANGEMENT IN NEONATES WITH ASPHYXIA NEONATORUM

Abstract

Background: Asphyxia (insufficient oxygen supply) can lead to severe hypoxic ischemic organ damage in newborns followed by a fatal outcome or severe life-long pathologies like renal insufficiency. In some particular cases it is difficult to discriminate between mild and severe asphyxia. Advanced methodology to improved diagnosis of birth asphyxia and prediction of individual short and long term outcomes obligatory needs to be developed

Materials & Methods: A total of 264 patients were included in the study as per inclusion criteria were included in the study. Main outcome variable was renal derangement in asphyxia neonatorum. It was noted in the Performa as well.

Results: Total neonates included in this study were 264 (100%) having mean of weight was 2.54 kg with standard deviation was 0.50 and having mean of APGAR score was 4.43 with SD 1.66. Out of 264 neonates, it was noted that 189 (71.6%) neonates were suffered from Renal derangement in which 109 (57.7%) were males and 80 (42.3%) were females with mean of weight was 2.53kg and standard deviation was 0.5 and having mean of APGAR score was 4.44 with standard deviation was 1.667.

Conclusion: We conclude that renal failure is a significant problem in asphyxiated neonates with majority of babies having nonoliguric failure. Severity of renal function abnormality correlates well with degree of asphyxia.

Keywords: Asphyxia Neonatorum, Renal Derangement, Apgar score, Low Birth Weight.