Sulfonic acid-functionalized silica: A remarkably efficient heterogeneous reusable catalyst for the one-pot multi-component synthesis of amidoalkyl naphthols

Abstract

A novel, efficient and one-pot method for preparation of amidoalkyl naphthol derivatives is reported using sulfonic acid-functionalized silica as an effective heterogeneous catalyst under thermal solvent-free conditions. This method has the advantages of high yields, a cleaner reaction, simple methodology, easy work-up and greener conditions. The catalyst is easily prepared, stable (up to 300 C, reusable and efficient under the reaction conditions.

Keywords: Amidoalkyl naphthols; Multicomponent synthesis; Solid acid; Sulfonic acid-functionalized silica; Heterogeneous recyclable catalyst