ICSI Cycle with a Sperm from TESE versus From Ejaculate in Oligospermic Men

Abstract

Objective: The aim of our study to compare the quality of embryos and fertilization rates in (ICSI) cycles using sperm from ejaculates of (oligospermic), and sperm of azospermic patients using (TESE).

Methods and Subject: Retrospective study, conducted (the IVF Unit) at KAUH, all male patients under went ICSI cycle from June 2011 until January 2012. Total number of ICSI cycle was 184 but only 53 male (27 with azospermia sperm obtained by TESE and 26 with oligospermia) were eligible for analysis by using inclusion and exclusion criteria. The medical record of the wives of male patients reviewed and information was obtained from the file . Number of Oocyte, and number of embryos transfer and quality of embryo recorded. Main Outcome Measure Quality of Embryo, Fertilization rates.

Result(s): 184 ICSI only 53 were eligible for analysis, divided into two group according to the orgain of the sperm Group 1 (27) had TESE and Group 2 (26) gave sperm by masturbation but their semen parameters count ?5×10⁶/ml and ?10% progressive motility. When compare the number of the embryo with the quality of grade (from 1 to 4) in both groups we found , the frequency of good quality embryo grade 1,2, were more in the oligospermic group than TESE and that was  statistically significant with P value 0.001.

Conclusion: The fertilization rates are not affected by the source of the sperm but the quality of embryos are Better with sperm retrieved from the ejaculate when compare with sperm from TESE.

Key Words: ICSI, Azospermia, TESE