Histological and Immunohistochemical Evaluation of Local Exogenous Application the of Green Tea on Bone Healing (Experimental Study on Rats)

Abstract

The study was designed to identify the role of local exogenous green tea in bone healing . Thirty male albino rats, were subjected for bone defects in medial sides of both tibia bone (right tibia was considered as experimental site with 1µl of extract green tea, while the left be the control one, (treated with 1µl of normal saline). The rats were scarified at 3,7,10 days post surgery. Bone healing was histologically examined with immunohistochemical for localization of bone morphogenic protein 2.The results: show bone healing treated with extracted green tea illustrated to be faster in apposition of ostoid and bone trabeculae that is detected to fill the most of bone defect in comparism with control group.Conclusion: Our results indicate that low application of  exogenous green tea  could be an effective therapeutic for bone injures, these data are promising  for a possible future clinical usage especially for enhancement of bone healing.