Extraction, Isolation, Characterization and Antibacterial Activity Test of an Alkaloid Constituent from Seeds of Calpurnia Aurea

Abstract

By different solvent extractions and chromatographic techniques an alkaloid constituent compound A1 was isolated from seeds of Calpurnia aurea. Infrared spectroscopy, mass spectroscopy and nuclear magnetic resonance studies showed that the isolated compound A1 was chemically: 1-(2,4-bis(dimethylamino)cyclopentyl)heptan-4-one, C₁₆H₃₂N₂O and the study revealed that the pure isolated compound have a wide range antibacterial activity (MIC of 25.8 to 78 mg/mL) against all tested bacteria strains.

Keywords: Calpurnia aurea; alkaloid; characterization; antibacterial activity.

DOI: 10.7176/JNSR/9-23-06

Publication date: December 31^st 2019