Comparative Antioxidant Effects of Two Separate Ethanolic Extracts Fed Female Albino Rats on Some Tissue Markers

Abstract

Garcinia kola and Curcuma longa possess antioxidant, anti-inflammatory and anti-toxic properties which makes them ideal choices in traditional alternative medicine. Kolaviron and curcumin ethanoic extracts are from Garcinia kola and Curcuma longa respectively and have shown ample beneficial health effect in animal models of diseases and also in the prevention of hepatoxicity induced by several toxins.  The aim of the study was to compare the separate effects of kolaviron and curcumin ethanoic extracts on blood parameters in female Wister albino rats.

Eighty-four female albino rats were used in this study and were grouped into fertile, infertile and pregnant rats in the investigation. Anti-oxidant markers such as catalase, superoxide dismutase (SOD), glutathione s-transferase (GST) were assayed for in this study.The result shows that both kolaviron and curcumin, possess antioxidant properties and the results from the three groups investigated, showed that the extracts had similar influence (anti-oxidants effect) on pregnancy, as kolaviron showed a bit more “potency”. In the infertile rats, both extracts present competing anti-oxidants effects on the organs. In conclusion, kolaviron presented a more effective anti-oxidants property across the three subject groups studied compared to curcumin.

Keywords: Garcinia Kola, Turmeric, Kolaviron, Curcumin, Haematological, antioxidants Parameters

DOI: 10.7176/JNSR/13-6-04

Publication date:March 31^st 2021