Effect Of Alcoholic Extract Of Costus speciosus Koen. on Aspergillus fumigatus in lab rats (II)

Abstract

This study was designed to find out the therapeutic efficiency of alcoholic extractof C.speciosus in the treatment of pneumonia caused  byfungus A.fumigatus, in the study (30) of male rats eggs Rattus norvegicus injury experimentally  two solution spores of a single dose of (25)lµ size and concentration of 10 7 units consisting of the colony / ml by distillation inside the nose. Results of the study pathological macroscopic and histopathological ability of fungus to the events of infection, pneumonia when an autopsy after (14 days) from injury was infiltration of cells of the inflammatory and the emergence of edema and emphysema, and after the onset of clinical symptoms of weakness and difficulty breathing during the first week of injury the second group were treated extract of the plant at a dose (75 mg / kg) daily for a period (21 days) with oral dosage using the tube stomach. And proved the results obtained from the study of histological sections impact the effective and positive role for the test in the treatment represented by a restoration of the lung tissue to be mounted typical natural.

Keywords: Costus speciosus , Aspergillus fumigatus ,  histological effects.