Evaluation and comparison: antipyretic activity in compound products of herbal pharmaceutical industries

Abstract

To reduce an elevated body temperature various antipyretics drugs and medicinal plants are used. This study was designed to evaluate the antipyretic claim compound herbal syrups manufactured by three different herbal pharmaceutical companies of Pakistan. Bukharin (Hamdard Laboratories), Fever-X (Qarshi Industries) and Bukharok (Ashraf Laboratories) products were tested in rabbits. The experimental conditions were produced by E. coli suspension in animal model whereas 150 mg/Kg Paracetamol suspension was used as positive control. Doses with concentration of 5 ml/Kg of syrup were administered to check temperature lowering effect. The administration of Bukharin, Fever-X and Bukhrok significantly reduced the rectal temperature of animals. It was concluded that Bukharok and Bukharin syrups are good antipyretic drug products as they lowered 3 and 2.5 ?C temperature respectively.

Keywords: Antipyretic effect, Herbal Syrups, Comparison with Allopathic Medicine