Synthesis, Characterization and Anti-hyperglycemic Activity of some novel Formazans Derivatives
Abstract
In the present investigation, a series of novel formazans 4[a – h]were synthesized by the condensation of Schiff bases2[a-c] and diazonium salt chloride of various substituted aromatic amines 3[a-c] . The intermediate Schiff bases (2a-2h) were itself synthesized by the condensation of different aromatic amines2( thiocarbohydrazide , nicotinic hydrazide , carbohydrazide) with various aromatic aldehydes1.The completion of reactions was checked by TLC.The structures of the formazan compoundswere identified by FT- IR ,1H-NMR , 13C- NMR and mass spectral studies. Newly synthesized compound was screened for their anti- hyperglycemiaactivity.
Keywords:: Formazans, Schiff bases Anti-hyperglycemic
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ISSN (Paper)2224-3224 ISSN (Online)2225-0956
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