The Antibacterial activity of new ethyl 2-oxo-2H-chromene-3-carboxylate complexes against bacteria isolate from wound infection in Baghdad city

Abstract

The related researches are based on preparation and mixed of some ligand complexes of the transitional metal ions [Cu(II), La (III)] with ethyl coumarin (ethyl 2-oxo-2H-chromene-3-carboxylate) , finally on the studies of antimicrobial (antibacterial) activities of the same. For their synthesis the prepared solutions of metal chlorides are allowed to react with an ethanolic solution of ethyl 2-oxo-2H-chromene-3-carboxylate in different ratio. Disc diffusion methods were employed for antimicrobial assays against four human pathogenic bacteria isolation from wound infection The bacterial properties of the metal complexes reveal that the Lanthanum complex is more effective against almost all antibacterial tested. Furthermore The staphylococcus aureus bacteria was more types of bacteria sensitive to the effect of the complex studied .

Key words: Antimicrobial activities, metal complexes, human pathogenic bacteria, wound infection