Cortisol levels, IFN-gamma and TNF-alpha in ischemic stroke patients

Abstract

Stress is one cause of stroke. Stroke is a disease that needs attention, given the increasing prevalence and cause of morbidity and mortality of patients. Model home care is an approach to holistic nursing care at home that emphasizes the intervention of bio-psycho-social-spiritual. This study aims to determine the effect of differences in the levels of cortisol, IFN-gamma and TNF-alpha before and after intervention between groups holistic model of home care and group home care. This research study design experiments with a model of the pre-post test group design and subjects were measured biological responses such as cortisol, IFN-gamma and TNF-alpha. The sample in this study were all patients with ischemic stroke who had been allowed to go home after hospitalization in room Seruni A Hospital Dr. Soetomo in 2009 and settled in the city of Surabaya consisting of 40 patients. The results showed differences in the levels of cortisol, IFN-gamma and TNF-alpha in patients after ischemic stroke before the homecare holistic intervention. There are differences in excess cortisol, IFN-gamma and TNF-alpha in patients with ischemic stroke who received care home model of care with a model of home care holistic.

Keywords : Cortisol, IFN-gamma and TNF-alpha