SYNTHESIS OF 4-BENZYLIDENE-2-(4-NITRO- PHENYL) - 4H-OXAZOL-5 -ONE DERIVATIVES WITH SUSPECTED BIOLOGICAL ACTIVITY
Abstract
Oxazolones are five membered heterocyclic compounds containing nitrogen and oxygen as heteroatoms.The C-2 and C-4 positions of the oxazolone are crucial for their various biological activities. A series of oxazolone derivatives (1-11) have been synthesized as potential antibacterial and fungal agent. The newly synthesized compounds were evaluated. compounds have been prepared by the condensation of 4-nitrobenzoylglycine or benzoyl glycine with aromatic aldehydes in the presence of ethanol, acetic anhydride and glacial acetic acid. The newly synthesized compounds were characterized by FTIR, ¹HNMR, C¹³NMR.
Keywords:- Oxazolone, antibacterial and fungal agent, Synthesis.
To list your conference here. Please contact the administrator of this platform.
Paper submission email: CMR@iiste.org
ISSN (Paper)2224-3224 ISSN (Online)2225-0956
Please add our address "contact@iiste.org" into your email contact list.
This journal follows ISO 9001 management standard and licensed under a Creative Commons Attribution 3.0 License.
Copyright © www.iiste.org