Synthesis, spectral and antimicrobial activity of mixed ligand complexes of Co(II), Ni(II), Cu(II) and Zn(II) with Anthranillic Acid and Tributylphosphine

Abstract

Mixed ligand complexes of bivalent metal ions, viz; Co(II), Ni(II), Cu(II) and Zn(II) of the composition [M(A)₂((PBu₃)₂]in(1:2:2)(M:A:(PBu3).  molar ratio, (where A^- Anthranilate ion ,(PBu3)= tributylphosphine. M= Co(II),Ni(II),Cu(II) and Zn(II).

The prepared complexes were characterized using flame atomic absorption, by FT-IR, UV/visible spectra methods as well as magnetic susceptibility and conductivity measurements. The metal complexes were tested in vitro against three types of pathogenic bacteria microorganisms: (Staphylococcus, Klebsiella SPP .and Bacillas)to assess their antimicrobial properties. Results. The study shows that all complexes have octahedral geometry; in addition, it has high activity against tested bacteria. Based on the reported results, it may be concluded that.The results showed that the deprotonated ligand(nthranilc acid ) to anthranilate ion (A^-) by using (KOH) coordinated to metal ions as bidentate ligand through the oxygen atom of the carboxylate group (-COO^-), and the nitrogen atom of the amine group (-NH₂), where the Tributylphosphine coordinated as a monodentate through the  phosphor atom.

Keywords :Mixed(anthranilic acid or tributylphosphine) complexes, spectroscopy studies, mixed ligands  and  Antibacterial Activities