Catalytic And Economic Method Using As Catalyst the I-Si(CH3)3 Generated During The Condensation Of Silylated Base With Natural Phosphate Doped With KI (NP/KI)

Driss Ouzebla, Hassan B. Lazrek, Michael Smietana, Jean-Jacques Vasseur

Abstract


Several D-ribonucleosides are prepared from 1-O-acetyl-2,3,5-tri-O-benzoyl-?-D-ribofuranoside  and trimethylsilylated nucleobases under mild conditions by using as catalyst I-Si(CH3)3 generated during the condensation of  silylated base with NP/KI.

Keywords: I-Si(CH3)3 generated during the condensation of silylated base with NP/KI,one-step synthesis, and D-ribonucleosides.


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ISSN (Paper)2224-3224 ISSN (Online)2225-0956

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