SYNTHESIS, Spectroscopic Characterization and Evaluation (Antibacterial & (GOT, G pT) Enzyme )Activity of Mixed Ligand Complexes of M(II) with Amino Acid (L-Asparagine) and Schiff Bases Derived from (Sulfamethoxazo Drug with 2,4Dimethoxybenzaldehyde)

Abstract

Mixed ligand  Mn(II),Co(II), Ni(II),Cu(II) , Zn(II), Cd(II) and  Hg(II)complexes with a bidendate  Schiff base prepared by condensation of (Sulfamethoxazo  Drug  With 2,4Dimethoxybenzaldehyde) as a primary ligand and  potassium asparaginate as secondary ligand  were synthesized and characterized on the basis of   molar conductance measurements, magnetic susceptibility values, UV-Vi s ,FT- IR, spectral data wherever possible. Electronic spectra and magnetic susceptibility measurement reveal octahedral geometry for   all M(II) complexes. The complexes are found to be non-electrolytic in nature on the basis of low molar conductance. The antibacterial activity of the free ligands HL and there metal complexes were tested against the bacterial ( E.coli, Staphylococcus aureus, Psedomonas and Acinetobactera)

Keywords:: biidendate, Schiff base, Antibacterial.