Intravenous Iron Sucrose Therapy in Anemia with Pregnancy

Abstract

Anemia of pregnancy is most common medical disorder in the developing country, affecting 2 billion population worldwide. In India prevalence is 49.7% of pregnancy contributing to 80% of maternal mortality. Parental iron therapy produces rapid, complete correction of iron deficiency including iron stores. Intravenous iron sucrose therapy has become gold standard in management. It has many advantages over other iron preparations in correction of anemia.AIMS AND OBJECTIVE: Evaluation of hemoglobin improvement, time required, and patient’s compliance after iron sucrose therapy.MATERIAL AND METHODS: Retrospective analysis was done of 264 pregnant women with anemia who were admitted in AL-Zahra Teaching Hospital from May 2015 to August 2019, and were diagnosed as iron deficiency anemia and had received intravenous iron sucrose 200 mg weekly till targeted hemoglobin 10gm was reached.RESULTS: majority of women (54.2%) were in age group of 21-29 years. 66.3% were resident of rural area. Anemia was more common (69.7%) in women with vegetarian diet. 83% 0f patients were multigravida. 48.9% cases were of mild, 44.7% of moderate, and 6.4% of severe anemia. There was initial rise in Hb within a week and rise of 1-2gm Hb per week attaining a targeted Hb. CONCLUSION: Iron sucrose is the best tolerated drug, gives mean Hb rise by 600 mg in all grades of anemia and in maximum periods of 4 weeks. Looking at the patient’s compliance and feasibility this drug has replaced strategy of unnecessary blood transfusions.

Keywords: Anemia of pregnancy, Pareneteral therapy, Iron sucrose therapy.

DOI: 10.7176/JHMN/81-07

Publication date:October 31^st 2020