A Study of Some Quality Characteristics of Paracetamol Tablet

Abstract

This paper is focused on the study of some quality characteristics of Paracetamol Tablet produced by TUYIL Pharmaceutical Industry Limited, Ilorin, Kwara State between January and June 2019. The data used was a secondary data collected from the quality department of the company, and collected on the following four quality characteristics: average weight (milligram), hardness (kilo pounds), disintegration time (minutes), and friability (percentage) as in the appendix. The Pattern of distribution was examined for the characteristics through their histogram and monitored using 16X"> -chart and R-chart. The process capability analysis was carried out by estimating the capability indexes. All the quality characteristics studied are in statistical control, capable of producing within their specified range. All the pairs of the quality characteristics are significantly correlated.

Keywords:Specification Limits, Upper Control Limit, Lower Control Limit, Statistical Process Control, Average Weight, Disintegration Time, Hardness, Friability

DOI: 10.7176/JHMN/95-03

Publication date: November 30^th 2021