Comparison between Ceftriaxone with Ceftriaxone and Metronidazole Combination in Maxillofacial Fracture (at KSM Reconstruction and Aesthetic Plastic Surgery, RSUD Dr. Soetomo)

Abstract

The purpose of the research is to evaluate infection rate on maxillofacial fracture in Plastic Surgery and Aesthetic at Dr.Soetomo General Hospital Surabaya, Indonesia, from January 2015 to December 2019. The research is an analytic descriptive study with retrospective cohort design. The affordable population were maxillofacial fracture patients with reconstructive treatment who were given therapeutic antibiotics, namely ceftriaxone at a dose of 2 x 1 g and metronidazole 3 x 500 mg intravenously. The collected data is then transferred to IBM Statistical Package for Social Sciences (SPSS) 20 software for statistical analysis with non-parametric statistics. Descriptive and analytical data will be presented in a series of texts and tables. A total of 621 patients medical record were obtained with a characteristic distribution based on gender, age, and history of trauma from 2015 to 2019 where total cases of postoperative infection after facial bone fracture reconstruction were 10 patients (1.61%), the incidence of infection with a single antibiotic ceftriaxone were 6 patients (0.97%) and cases in the administration of combination of antibiotics ceftriaxone, metronidazole were 4 patients (0.64%). The incidence of post-operative infection for facial fracture reconstruction given single ceftriaxone antibiotics was higher than that given the combination of ceftriaxone, metronidazole at KSM Reconstructive and Aesthetic Plastic Surgery, Dr. Soetomo General Hospital, Surabaya, Indonesia from 2015 until 2019.

Keywords: ceftriaxone-metronidazole, infection, maxillofacial fracture

DOI: 10.7176/JHMN/97-03

Publication date: January 31^st 2022