Evaluation of the Ratio of Monocyte / HDL Cholesterol in Psoriasis Patients

Abstract

The present study aims to investigate the monocyte to high-density lipoprotein cholesterol ratio (MHR) for the psoriasis patients and the correlation between MHR and Psoriasis Area and Severity Index (PASI) score. This study consisted of 96 psoriasis patients and 64 healthy individuals. Clinical properties and PASI scores of the patient group were recorded. Serum CRP and MHR were evaluated in both groups. The level of MHR was significantly higher in psoriasis patients than the control group (p:0.001). A significant positive correlation between MHR and PASI scores of the patients were detected. Increased level of Serum CRP was observed in psoriasis patients but is not associated with the PASI score. Furthermore, MHR and CRP had statistically insignificant positive correlation. To conclude, our findings indicate that high MHR values are significantly and independently related to the presence of psoriasis. In addition, considering the findings, we think that MHR can be used as an indicator of the severity of the disease for psoriasis.

Keywords: Psoriasis, Monocyte to HDL ratio, PASI.

Special Issue of Health Sciences

DOI: 10.7176/JSTR/6-03-22